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Alliance for the Prudent Use of Antibiotics (APUA) is now under the auspices of the International Society of Antimicrobial Chemotherapy (ISAC)


Stuart Levy’s prophetic warnings (made during an era of plentiful antibiotics) about antibiotic overuse and the emergence of resistance have come to full fruition. He co-founded and led APUA for 37 years: it was the first organisation to address antibiotic preservation and continues to provide a strong voice in the field despite the subsequent emergence of many other organisations and groups addressing a topic which has become a specialty in its own right; that of “antibiotic stewardship”. Towards the end of last year, Stuart Levy’s retirement from APUA and Tufts University School of Medicine in Boston was announced. He was a trailblazer and, in APUA, leaves a very strong legacy.

Stuart’s retirement was an opportunity for the APUA Board to review its leadership and governance and it took the opportunity to seek a partner organisation with which to synergise. This led to the merger of APUA with the International Society of Antimicrobial Chemotherapy (ISAC), effective from February 2019. ISAC was founded as a charity in 1961 and, in response to the dynamic nature of the subject matter, has focused most recently on antimicrobial stewardship and antimicrobial resistance.


The boards of the ISAC Antimicrobial Stewardship Working Group and APUA have merged to form the following new APUA Board:


APUA Chair
Pierre Tattevin
APUA Vice-Chair
Geoff Coombs
APUA Secretary
Mushira Abdulaziz Enani
(Saudi Arabia)
R. Gaynes
A. Ghafur
S. Gharakhanian
S. Kanj
C. Larkin
G. Levy Hara
F. MacKenzie
P. Riley
R. Saginur
D. White


  • The continuing mission of APUA is to maximise the effectiveness of antimicrobial treatment by promoting appropriate antimicrobial use and containing drug resistance.
  • APUA and ISAC will retain their own identities.
  • The launch of APUA under the auspices of ISAC will be kick started with a joint newsletter and reception during ECCMID in Amsterdam in April and the announcement of a new plan of work for APUA.
  • Please contact for further information.


Visit for more information.


Last updated: May 16th-2019