Working Groups

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Current Officers

K Tateda


Kazuhiro Tateda


Paul Anantharajah Tambyah

S Kamiya


Shigeru Kamiya

P Tenke


Peter Tenke

All Members

Truls E. Bjerklund Johansen (Denmark)
Yong-Hyun Cho (Korea)
Ryoichi Hamasuna (Japan)
Seung-Ju Lee (Korea)
Tetsuro Matsumoto (Japan)
Takehiko Sho (Japan)
Satoshi Takakashi (Japan)

How to Join

ISAC Working Groups are open to new members with a strong interest and relevant experience in the given field. To join an ISAC Working Group, please contact Fee Johnstone, ISAC Executive Officer with your name and a brief C.V. We welcome new members!

Aims and Objectives

Bacteria survive in nature by forming biofilm on surfaces, not only implanted devices but also human organ tissues. Biofilm growing bacteria cause chronic infections including device-related infections. Pathogenic bacteria forming biofilm are able to escape from both phagocytosis by mainly polymorphonuclear leukocyte and macrophages and action of antimicrobial agents. Therefore, clinical treatment of patients with device-related infections and biofilm diseases is currently not simple. The increasing knowledge about the nature and properties of biofilm growing bacteria is the basis for efficient prophylaxis, diagnosis and treatment of device-related infections and biofilm diseases. Further progress will rely on comprehensive efforts in basic, applied and clinical research.

This Working Group aims to:

  • Clarify the molecular mechanisms of biofilm formation by pathogenic bacteria.
  • Enhance the epidemiological surveillance of device-related infections and biofilm diseases.
  • Examine the correlation between biofilm formation and bacterial pathogenesis.
  • Establish the diagnostic procedure for chronic biofilm infections.
  • Develop promising strategies for the treatment of patients with device-related infections and biofilm diseases.

The Working Group has written the following Work Plan:

  • To organize educational meetings on bacterial pathogenesis and biofilm formation, epidemiology of device-related infections and biofilm diseases, microbiological diagnostic procedures and use of conventional and newly available drugs.
  • Promote a network to collect data from the research laboratories to evaluate the epidemiology, etiology and therapeutic agents.
  • To develop new strategies including use of biofilm-dissolving compounds and quorum sensing inhibitors for the treatment of patients with device-related infections and biofilm diseases.

Topics covered by this group include: 

  • Antimicrobial agents
  • Bacterial pathogenesis
  • Biofilm diseases
  • Clinical microbiology
  • Device-related infections
  • Epidemiology
  • Genetics
  • Molecular diagnosis
  • Pathology
  • Pharmacology


June 2013 Symposium: “Development of anti-quorum sensing therapy for device-related infections and biofilm diseases” at the 27th ISC, Yokohama, Japan.
October 2011 Symposium: ”Biofilm and Bacterial Pathogenesis” at the Joint Symposium of International Society for Chemotherapy Working Group “Device-related Infection and Biofilm” and West Branch of Japanese Association of Infectious Diseases, Kitakyushu, Japan.

Projects / Publications


Last updated: November 28th-2019