Working Groups

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Membership

Current Officers

Chairperson

Jian Li

Vice-Chair

Gauri G. Rao

Secretary

Zackery P. Bulman

Treasurer

Jaime Lora-Tamayo

Early Career Officer

Sue Nang

All Members

Ayhan Akbulut (Turkey)
Tomefa Asempa  (USA)
Prapthi Bathani (India)
Christian Eckmann (Germany)
Evangelos J. Giamarellos-Bourboulis (Greece)
Joan Gomez Junyent (Spain)
Ian Gould (UK)
Zhihui Hao (China)
Yanqin Huang (USA)
Khalid Iqbal (Germany)
Farha Arakkaveettil Kabeer (China)
Adrian Khoei (USA)
Maria Koliou (Cyprus)
Teresita Mazzei (Italy)
Andrea Novelli (Italy)
Gargi Patel (USA)
Federico Pea (Italy)
Gianpaolo Perletti (Italy)
Francesco Scaglione (Italy)
Stelvin Sebastian (India)
Ameer Shajahan (India)
Fekade B. Sime (Australia)
Kazuhiro Tateda (Japan)
Ursula Theuretzbacher (Austria)
Paul M. Tulkens (Belgium)
Tony Velkov (Australia)
Florian Wagenlehner (Austria)
Minggui Wang (China)

 

Aims and Objectives

Over the last 20 years, we assisted in an emerging crisis of antibiotic resistance for microbial pathogens throughout the world, at the very moment when increasing antimicrobial resistance has created the development of new antibiotics with novel mechanisms of action lacking. In this era the optimal use of old and eventually new antimicrobials became mandatory. The appropriate use of antimicrobials based on their pharmacological properties, including pharmacokinetic/pharmacodynamics (PK/PD) relationship, is one way to achieve clinical success. By using pharmacological information researchers, regulators and clinicians can achieve the goal of maximal therapeutic effect while reducing the risks of drug exposure-related adverse events as well as the selection of resistance. While this is now more and more recognized by Academia, Industry and Regulatory Agencies, there is presently a lack of training into these disciplines. The same applies to other areas of development of anti-infectives such as antiviral, antifungal and antiprotozoal. 

This Working Group aims to promote international exchange of ideas and new research into all aspects of anti-infective pharmacology, also in collaboration with other scientific societies.

Work Plan for the group is as follows: 

• To reach out and encourage ID physicians, pharmacists, scientists and students in PK/PD and drug discovery worldwide, in particular in Asian (e.g. Great China, Malaysia, Singapore, Japan, South Korea) and Oceanian countries.

• To set up three major networks within the WG:

o PK/PD
o Computational pharmacology
o Systems pharmacology and bioinformatics

• To establish partnership with other key antimicrobial societies, such as the International Society of Pharmacometrics (ISoP)

• The Working Group will present at three sessions during the International Congress of Antimicrobial Chemotherapy (ICC) in Perth, Australia (27 - 30 November 2022)

• To organise webinars and young investigator activities in 2022

• 1st International Conference on Antimicrobial Computational Pharmacology in Melbourne, Australia (7 – 9 December 2022)

 

Webinars

Phage pharmacology & therapy
December 2023

 

Journey into the anti-infective field: academic, clinical and industry perspectives
January 2023

 
The group held the following free webinars in 2021:

 Clinical Trials Targeting Antimicrobial Resistance

Speakers - Prof. David Paterson, Dr Mo Yin, Associate Prof. David Lye


The following webinars were organised in collaboration with the China Agricultural University

New roles of beta-lactamese enzymes

Speaker - Prof. Jean-Marc Rolain


Insights of antimicrobial therapy in biofilm-associated infections: the clinical paradigm of prosthetic joint infections

Speaker - Dr Jaime Lora-Tamayo

Projects / Publications

  1. The Working Group published a special theme issue in 2021 on antimicrobial PK/PD in International Journal of Antimicrobial Agents (IJAA) edited by Profs Jian Li and Jason Roberts: Antibiotic PK/PD: Where
    are we heading
    On behalf of our working group, this special themed issue also serves as a tribute and memorial to four anti-infective gurus who recently passed away, namely Professors Alan Forrest (1952-2018), Johan Mouton (1956-2019), Donald Kaye (1931-2019) and Hartmut Derendorf (1953-2020).

  2. Collaborating with the International Society of Anti-Infective Pharmacology, we are preparing a position article “Future of Antibiotic Research” which is under review with Lancet Infectious Diseases. Zackery Bulman is a leading author.

  3. Associate Partner in the project DRIVE-AB (Driving Reinvestment in R&D and Responsible Antibiotic Use). DRIVE-AB is a public-private consortium funded by the EU Innovative Medicines Initiative (IMI) and part of the New Drugs for Bad Bugs (ND4BB) programme. Drive Website

  4. Established partnership with the International Society of Anti-Infective Pharmacology (ISAP).

  5. Prof Jian Li has established a global initiative for antimicrobial computational pharmacology with Prof Falk Schreiber (Germany), and the 1st International Conference on Antimicrobial Computational Pharmacology was held on 1-4 Dec 2020 which is co-organised by the working group and ISAP.

Past Events

December 2022 1st International Congress on Antimicrobial Computational Pharmacology
Co-organiser with International Society of Antimicrobial Pharmacology (ISAP)
November 2022 Workshop at the International Congress of Antimicrobial Chemotherapy (ICC)
Perth, Australia
Introduction to Pharmacokinetics/Pharmacodynamics: A Basic Primer
27-30 June 2015 Summer School on Anti-Infective Pharmacology, Italy
6-9 June 2013 Symposium for the 28th ICC in Yokohama, Japan
8-11 Nov 2012 Symposium at the 3rd SEEC in Dubrovnik, Croatia
November 2011 Symposium at the 2nd SEEC in Belgrade, Serbia
7-10 May 2011 Symposium at the 21st ECCMID/17th ICC in Milan, Italy with the ESCMID PK/PD of Anti-Infectives Study Group (EPASG) and the ISC Working Group: Antimicrobials of the Future
September 2010 Summer School on Anti-Infective Pharmacology, Palazzo Feltrinelli, Gargnano, Italy

 

Last updated: February 8th-2024