IJAA Editor's Choice

The Editor in Chief of the International Journal of Antimicrobial Chemotherapy, Prof. Jean-Marc Rolain, and his Scientific Assistant, Sophie Baron, have selected the following article for the Editor's Choice section.

You can read it for free for a limited time!

1. Essential and Forgotten antibiotics: an inventory in low- and middle-income countries.

Editor's comment:

"Faced with the emergence of multidrug-resistant (MDR) bacteria, particularly bacteria belonging to the ESKAPE group, it is important to evaluate access to first-line antibiotics (also called “Access” antibiotics) and those used in case of infection caused by MDR bacteria (also called “Forgotten” antibiotics). The use of appropriate antibiotic therapy and the rapid access to this antibiotic are two essential elements for patient survival and to limit the selection of MDR strains. The availability of these antibiotics is poorly known in low- and middle-income countries. The authors of this work carried out a questionnaire to identify antibiotics available in 28 low- and middle-income countries, including 11 from Africa, 11 from Asia and 6 from America. Two-thirds of the participating countries have at their disposal the 26 antibiotics belonging to the WHO-EML "Access" list. On the other hand, only cefepime, belonging to the list of "forgotten" antibiotics, was available in more than two third of the participating states. These results are partly comforting because most countries have access to first-line antibiotics. On the other hand, while some countries are facing an increase in the level of antibiotic resistance, they have few alternatives in case of infection caused bacteria resistant to first line antibiotics. In addition, they use broad-spectrum antibiotics more easily, as targeted antibiotics are not available. These results represents a first inventory of the availability of antibiotics in these countries and will pave the way for new antibiotics approvals to increase the therapeutic arsenal available for infectious diseases."


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